NER 2011 Paper Abstract


Paper ThDT1.3

Wu, Dan (Johns Hopkins University), Bezerianos, Anastasios (University of Patras), Sherman, David (Infinite Biomedical Technologies), Jia, Xiaofeng (Johns Hopkins School of Medicine), Geocadin, Romergryko (Johns Hopkins University), Thakor, Nitish (Johns Hopkins University)

Causal Interactions from Thalamic and Cortical LFPs Following Hypoxic-Ischemic Brain Injury

Scheduled for presentation during the Poster Session "Poster I: Clinical Neural Engineering" (ThDT1), Thursday, April 28, 2011, 15:00−16:30, Room T1

5th International IEEE EMBS Conference on Neural Engineering, April 27 - May 1, 2011, Cancun, Mexico

This information is tentative and subject to change. Compiled on July 15, 2018

Keywords Clinical Neural Engineering - Neurological Disorders & Neurophyiology, Neural Signal Processing and Modeling


Asphyxial cardiac arrest (CA) introduces a global hypoxic-ischemic insult to the brain and disturbs the neural networks. We analyzed the thalamocortical interactions in a rat model of asphyxial CA, using the local field potentials recorded from the thalamus and cortex during CA and the recovery phase. The direct Directed Transfer Function (dDTF) and Directed Information Flow (DIF) were applied to characterize the causal coherence and causal mutual information of the network, respectively. Key results from dDTF and DIF analyses suggest from complementary perspectives that the thalamus may play a leading role in arousal from an ischemic brain.



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